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Conclusions: We found that CCL14 levels remained stable over 24 h in most patients undergoing cardiac surgery. However, the level of CCL14 at any time point was strongly associated with the risk of postoperative acute kidney injury (PS-AKI). Patients with high CCL14 levels had the highest risk of PS-AKI, while those with low CCL14 levels throughout the study period had the lowest risk. Therefore, clinicians can use a single CCL14 measurement to assess the prognosis of patients after cardiac surgery, but repeated measurements may provide more accurate information over time. 061ffe29dd